INDIAN KNOWLEDGE SYSTEM OF USING ILLICIUM VERUM.L WOUND HEALING IN DIABETIC FOOT ULCER – A TRADITIONAL APPROACH

Abstract

Since its beginning, Indian Traditional Medicine, the cornerstone of the world's ancient medical practice, has been vital to human health and well-being. Traditional medicine in India refers to the use of medicines that are believed to have Indian origins or that were imported to India and assimilated into Indian culture. Ayurveda, Siddha, Unani, Yoga, Naturopathy, and Homoeopathy are just a few examples of the country's recognized traditional medicine. The need for natural products and plant-based medications is rising globally these days. Herbal preparations can be used for extended periods of time due to their non-toxic nature, which also makes them potentially more effective than conventional medications. This study investigated the phytochemical, antioxidant, and antimicrobial effects of Illicium verum.L. Phytochemical analysis, total antioxidant capacity, DPPH radical scavenging effect, Nitric oxide scavenging, Hydrogen peroxide radical scavenging were studied by established methods. Antibacterial, antifungal effects were screened by disk diffusion respectively Significant (P <0.05) IC50 values compared to respective standards were recorded in DPPH radical scavenging (54.141µg/ml), Nitric oxide scavenging (93.542 µg/ml), Hydrogen peroxide radical scavenging (93.542 µg/ml) methods. In antibacterial screening, the extract showed significant (P <0.05) zone of inhibitions compared to positive controls Chloramphenicol against Gram Positive Enterococcus faecalis and Staphylococcus aureus and Gram negative Escherichia coli and Klebsiella pneumoniae. In antifungal assay, the greater zone of inhibition was obtained for growth of Candida albicans.